Monday, January 11, 2016

Key Givens


  • Rosalind Frankin - 30's. Jewish.
  • Maurice Wilkins - 30's/40's.
  • Ray Gosling - 20'.
  • James Watson - Early 20's.
  • Francis Crick - 30's/40's. His hair is amazing/crazy.
  • Randall, aka Sir John Turton Randall
         b. 1905 (46 - 48 years of age). Led the King's College London team. Wilkins is his deputy.
  • Linus Pauling
         
    (February 28, 1901 – August 19, 1994)[4] was an American chemist, biochemist, peace activist, author, and educator. He published more than 1200 papers and books, of which about 850 dealt with scientific topics.[5] New Scientist called him one of the 20 greatest scientists of all time,[6] and as of 2000, he was rated the 16th most important scientist in history.[7] 
    For his scientific work, Pauling was awarded the Nobel Prize in Chemistry in 1954. Pauling also worked on DNA's structure, a problem which was solved by James Watson, Francis Crick, Rosalind Franklin and Maurice Wilkins.[10]
  • William Bragg 
         (31 March 1890 – 1 July 1971) was an Australian-born British physicist and X-ray crystallographer, discoverer (1912) of Bragg's law of X-ray diffraction, which is basic for the determination of crystal structure. He was joint winner (with his father, William Henry Bragg) of the Nobel Prize in Physics in 1915: "For their services in the analysis of crystal structure by means of X-ray",[3] an important step in the development of X-ray crystallography.
    Bragg was knighted in 1941.[4] As of 2016, Lawrence Bragg is the youngest ever Nobel Laureate in physics, having received the award at the age of 25 years.[5]  Bragg was the director of the Cavendish Laboratory, Cambridge, when the discovery of the structure of DNA was reported by James D. Watson and Francis Crick in February 1953.
  • Odile Crick.  Wife of Francis Crick.

Takes place between 1951 & 1953.

It is "particularly cold in London, January 1951" - Wilkins

Wilkins & Crick = BFFs.
Crick's new co-worker is Watson, who Wilkins also has a work crush on.

"The Jews can be very ornery." - Watson

Behind her back, the doctors call her Rosy.

Watson says Rosalind's handshake is too firm, that there is nothing gentle, nothing remotely tender about her.

Wilkins, of the U.S., "theft and burglary are upheld as virtues", it's "turning its sinners into saints".

Wilkins + wife + son = :(

Wilkins is "unhappy" about Don's arrival.

Wilkins says Rosalind has been distracted since Don's arrived. Don says she was not.

Watson & Crick's new conclusion is that DNA consisted of TWO chains running in opposite directions, a pair of endless spirals that will work together but will never meet. This is how it replicates. How it works. Each strand is a template and in each template is another helix and on and on forever.

Mid-February, when they are close to cracking the secret of life, Watson and Crick invite everyone but Gosling to Cambridge. They are particularly cheerful. Everyone can see that Don is in love with Rosalind at this event.

Watson and Crick struggled with how the 4 bases fit into the picture. Did they pair? Work together? Or were they distinct from each other?

February 28, 1953 is the evening Watson and Crick crack the secret and the same evening Don and Rosalind go on their date to an Italian restaurant. Rosalind is taken to the hospital and diagnosed with ovarian tumors later that evening.

From 1956 onwards, Franklin battled with numerous tumors - possibly due to her work with radiation sources in an era before they were at their safest. She took ill and died April 16, 1958 from secondary illness related to her ovarian cancer. It was only after her death that allegations of sexism began to arise. As Crick and Watson's fame grew for solving the great "mystery of life," Franklin's contribution became difficult to ignore - although it would have been difficult to properly cite it in the literature anyway, as Franklin had mostly kept Photo 51 hidden from Wilkins and never published it.

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