Monday, January 11, 2016

Terms Explained

Photograph 51: 
The nickname given to an x-ray diffraction image of DNA taken by Raymond Gosling in May 1952, working as a PHD student under the supervision of Rosalind Franklin at King's College, London in Sir John Randall's group. It was critical evidence in identifying the structure of DNA.

**It confirm the double helical/ anti-parallel structure of DNA**



Cavendish Laboratory:The Cavendish Laboratory is the Department of Physics at the University of Cambridge, and is part of the School of Physical Sciences. The laboratory was opened in 1874 on the New Museums Site as a laboratory for experimental physics.

https://en.wikipedia.org/wiki/Cavendish_Laboratory

DNA: "Nucleic acid is a macromolecule composes of chains of mono-numeric nucleotides. This nucleic acid, or DNA, exists in 2 forms -



an A form and a B form (and now, we know, a Z form)." - Dr. Rosalind Franklin
DNA absorbs lots of water (H2O)

PHOSPHATES:
The phosphates exist on the outside of the molecule.

A phosphate group consists of a central phosphorous surrounded by four oxygens.
The phosphorous is single-bonded to three of the oxygens and double-bonded to the fourth. Due to the nature of the chemical bonds, there is a negative charge on each oxygen that has only one bond coming off of it. This negative charge accounts for the overall negative charge on the phosphate backbone of a DNA molecule.
Phosphates 
can carry energy, shape your cell membranes, and help form the backbone of your DNA


AGCT:
(A) adenine (larger)
(G) guanine (larger)
(C) cytosine (smaller)
(T) thymine (smaller)

(A) pairs with (T). (G) pairs with (C).

CYCLOTRON
cyclotron is a type of particle accelerator invented by Ernest O. Lawrence in 1932 in which charged particles accelerate outwards from the centre along a spiral path. The particles are held to a spiral trajectory by a static magnetic field and accelerated by a rapidly varying (radio frequency) electric field.

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